最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
首頁>>免疫學(xué)>>一抗>>DTX3L蛋白抗體
DTX3L蛋白抗體
  • 產(chǎn)品貨號:
    BN40447R
  • 中文名稱:
    DTX3L蛋白抗體
  • 英文名稱:
    Rabbit anti-DTX3L Polyclonal antibody
  • 品牌:
    Biorigin
  • 貨號

    產(chǎn)品規(guī)格

    售價(jià)

    備注

  • BN40447R-100ul

    100ul

    ¥2360.00

    交叉反應(yīng):Human,Mouse,Rat(predicted:Rabbit) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,ELISA

  • BN40447R-200ul

    200ul

    ¥3490.00

    交叉反應(yīng):Human,Mouse,Rat(predicted:Rabbit) 推薦應(yīng)用:IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱DTX3L
中文名稱DTX3L蛋白抗體
別    名B lymphoma and BAL associated protein; B-lymphoma- and BAL-associated protein; BBAP; Deltex 3 like; DTX 3L; DTX3L; DTX3L_HUMAN; E3 ubiquitin-protein ligase DTX3L; Protein deltex 3 like; Protein deltex 3 like protein; Protein deltex-3-like; Rhysin 2; Rhysin-2; Rhysin2.  
研究領(lǐng)域細(xì)胞生物  鋅指蛋白  表觀遺傳學(xué)  泛素  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Rabbit, )
產(chǎn)品應(yīng)用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量83kDa
細(xì)胞定位細(xì)胞核 細(xì)胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human DTX3L:651-740/740 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹DTX3L functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009]

Function:
Ubiquitin ligase that mediates monoubiquitination of 'Lys-91' of histone H4 (H4K91ub1), in response to DNA damage. Protects cells exposed to DNA-damaging agents. The exact role of H4K91ub1 in DNA damage response is still unclear but it may function as a licensing signal for additional histone H4 post-translational modifications such as H4 'Lys-20' methylation (H4K20me). Involved in the recruitment of 53BP1/TP53BP1 to sites of DNA damage by mediating H4K91ub1 formation.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the Deltex family.
Contains 1 RING-type zinc finger.

SWISS:
Q8TDB6

Gene ID:
151636

Database links:

Entrez Gene: 151636 Human

Entrez Gene: 209200 Mouse

Omim: 613143 Human

SwissProt: Q8TDB6 Human

SwissProt: Q3UIR3 Mouse

Unigene: 518201 Human

Unigene: 390852 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications










image.png

image.png

image.png

image.png

image.png

image.png