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驅動蛋白家族成員2A抗體
  • 產品貨號：
    BN40482R
  • 中文名稱：
    驅動蛋白家族成員2A抗體
  • 英文名稱：
    Rabbit anti-KIF2A Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產品規(guī)格

    售價

    備注

  • BN40482R-100ul

    100ul

    ￥2360.00

    交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Sheep) 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA

  • BN40482R-200ul

    200ul

    ￥3490.00

    交叉反應：Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Sheep) 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱KIF2A
中文名稱驅動蛋白家族成員2A抗體
別    名HK2; kif2; Kif2a; KIF2A_HUMAN; Kinesin 2; Kinesin heavy chain 2; Kinesin heavy chain member 2; Kinesin heavy chain member 2A; Kinesin like protein KIF2A; Kinesin-2; Kinesin-like protein KIF2A; kns2; M Kinesin; M-Kinesin.  
研究領域細胞生物  免疫學  神經生物學  信號轉導  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse, Rat,  (predicted: Human, Chicken, Dog, Pig, Cow, Horse, Sheep, )
產品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量80kDa
細胞定位細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human KIF2A:611-706/706 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產品介紹The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Function:
Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.

Subcellular Location:
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm > cytoskeleton > spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1.

Similarity:
Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily.
Contains 1 kinesin-motor domain.

SWISS:
O00139

Gene ID:
3796

Database links:

Entrez Gene: 3796 Human

Entrez Gene: 16563 Mouse

Entrez Gene: 84391 Rat

Omim: 602591 Human

SwissProt: O00139 Human

SwissProt: P28740 Mouse

SwissProt: Q9WV63 Rat

Unigene: 558351 Human

Unigene: 355686 Mouse

Unigene: 17829 Rat

Unigene: 218992 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.