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LULL1蛋白抗體
  • 產(chǎn)品貨號：
    BN40492R
  • 中文名稱：
    LULL1蛋白抗體
  • 英文名稱：
    Rabbit anti-LULL1/TOR1AIP2 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40492R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40492R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱LULL1/TOR1AIP2
中文名稱LULL1蛋白抗體
別    名TOR1AIP2; IFRG15; Interferon responsive gene 15; LULL1; Lumenal domain like LAP1; NET9; RP11-12M5.5; TOR1AIP2; Torsin 1A interacting protein 2; Torsin A interacting protein 2.  
研究領域細胞生物  免疫學  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量51kDa
細胞定位細胞核 細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human LULL1:221-320/470 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹LULL1 is a 470 amino acid endoplasmic reticulum single-pass membrane protein belonging to the TOR1AIP family. LULL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticulum (ER) and nuclear envelope (NE) of higher eukaryotes. LULL1 regulates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in the gene encoding torsinA. The gene encoding LULL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Function:
Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope.

Subunit:
Interacts with TOR1A and TOR1B (ATP-bound).

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane.

SWISS:
Q8NFQ8

Gene ID:
163590

Database links:

Entrez Gene: 163590 Human

Entrez Gene: 304881 Rat

Omim: 614513 Human

SwissProt: Q8NFQ8 Human

SwissProt: Q6P752 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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