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MED18蛋白抗體
  • 產(chǎn)品貨號(hào)：
    BN40536R
  • 中文名稱(chēng)：
    MED18蛋白抗體
  • 英文名稱(chēng)：
    Rabbit anti-MED18 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號(hào)

    產(chǎn)品規(guī)格

    售價(jià)

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  • BN40536R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep,Rhesus monkey, Gorilla, Catfish, Orangutan, Platypus) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF

  • BN40536R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep,Rhesus monkey, Gorilla, Catfish, Orangutan, Platypus) 推薦應(yīng)用：IHC-P,IHC-F,ICC,IF

產(chǎn)品描述

英文名稱(chēng)MED18
中文名稱(chēng)MED18蛋白抗體
別    名FLJ20045; hMED 18; hMED18; Human Mediator of RNA Polymerase II Transcription; MED 18; med18; MED18_HUMAN; Mediator complex subunit 18; Mediator of RNA polymerase II transcription subunit 18; Mediator of RNA polymerase II transcription subunit 18 homolog; OTTHUMP00000003645; p28b; TRAP/mediator complex subunit p28b.  
研究領(lǐng)域轉(zhuǎn)錄調(diào)節(jié)因子  結(jié)合蛋白  表觀(guān)遺傳學(xué)  
抗體來(lái)源Rabbit
克隆類(lèi)型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, Rhesus monkey, Gorilla, Catfish, Orangutan, Platypus)
產(chǎn)品應(yīng)用IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量24kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MED18:31-130/208 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

Function:
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the Mediator complex subunit 18 family.

SWISS:
Q9BUE0

Gene ID:
54797

Database links:

Entrez Gene: 540695 Cow

Entrez Gene: 54797 Human

Entrez Gene: 67219 Mouse

Entrez Gene: 393306 Zebrafish

Omim: 612384 Human

SwissProt: Q0VCD4 Cow

SwissProt: Q9BUE0 Human

SwissProt: Q9CZ82 Mouse

Unigene: 479911 Human

Unigene: 45929 Mouse

Unigene: 19506 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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